Help Researchers Expand Treatment Options For People with Sickle Cell Disease
Learn more to see if you may be eligible to participate in this research study.
About The Study Drug (Pociredir)
•On the other hand, fetal hemoglobin doesn’t cause sickling of the red blood cells and works fine for oxygen transport.
•In a person with Sickle Cell Disease, making more fetal hemoglobin can improve the symptoms of SCD, and can make the disease less severe.
•Pociredir acts to increase the amount of fetal hemoglobin made in red blood cells.
Why Consider Participating in a Clinical Trial?
If you decide to see if you qualify to take part in the study, you will help to advance the scientific understanding of SCD, and potentially improve future medicines for other people with SCD. There may be no direct benefit to you. People who are able to join the study will receive study-related tests and procedures at no cost. All research has some risks. The study team will talk with you about risks and answer any questions.
Am I Eligible?
You may be eligible to participate in this clinical research study if you:
•Are between 18 and 65 years of age
•Have been diagnosed with Sickle Cell Disease (SCD)
•Have previous experiences with hydroxyurea for at least 6 months at the highest dose possible, and it has not been effective, or you were unable to take hydroxyurea for reasons specified by your doctor.
Note: These are not the only eligibility criteria for this clinical research study, and other criteria may impact your ability to participate. A clinical research team member will help determine if you meet all necessary criteria to participate.
Medical Care During The Study
Taking part in this study is your choice. Whether or not you decide to participate will not change your regular medical care. We suggest you talk to family, caregivers, doctors, and the study team about taking part in this study and whether it is right for you.
What to expect at the start of the clinical trial If you decide to take part in the study, the study doctor will take a series of
measurements early in the study. These measurements include:
•Review of medical history and SCD symptoms
•Review of medications
•Physical examination
•Heart rate and blood pressure
•Heart activity
•Blood sample
Urine collection
Participants will receive the study treatment, tests and procedures at no cost. Daily compensation will be provided
About Clinical Trials
Before a new treatment or medicine is available to the public, it is first tested in a series of carefully regulated clinical trials. All clinical trials must be reviewed and approved by committees responsible for ensuring that studies are ethical, and that the rights and privacy of study participants are protected.
